Hundreds of women with breast cancer should be tested for an aggressive form of disease resulting from a genetic defect, according to new research.
Women with BRCA1 mutations are more likely to develop breast cancer, but also higher risk of ovarian cancer.
These patients have up to a 65 percent chance of developing breast cancer by the time they are 70 and 40 per cent chance of ovarian cancer.
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The researchers now argue that all women under 50 diagnosed with triple negative breast cancer should also be tests for faults in the gene BRCA1.
This could also be detected hundreds of women each year who can benefit from tailored treatment for breast cancer in BRCA1, such as platinum-based chemotherapy.
Clinical trials in radiotherapy have also suggested a certain type of radiation therapy would benefit women with BRCA1 mutations than others.
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Tuesday, February 14, 2012
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